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VLA4 inhibition

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Sickle Cell Disease Trial in Saint Louis (Motixafortide, Natalizumab, Leukapheresis)

Not yet recruiting
  • Sickle Cell Disease
  • Saint Louis, Missouri
    Washington University School of Medicine
Nov 8, 2022

Seborrheic Dermatitis, Papulopustular Rosacea Trial in New York (PF-07038124, Placebo Ointment)

Recruiting
  • Seborrheic Dermatitis
  • Papulopustular Rosacea
  • New York, New York
    Icahn School of Medicine at Mount Sinai
Aug 22, 2023

Breast Cancer Trial in Ottawa, Toronto (Arm A: Cemiplimab, Arm B: Cemiplimab + Dupilumab)

Not yet recruiting
  • Breast Cancer
  • Arm A: Cemiplimab, Arm B: Cemiplimab + Dupilumab
  • Ottawa, Ontario, Canada
  • +1 more
Jul 22, 2023

Inhibition of Autophagy Synergizes Anti-tumor Effect Trial in Guangzhou (100mg bid dose of hydroxychloroquine combined with

Recruiting
  • Inhibition of Autophagy Synergizes Anti-tumor Effect
  • 100mg bid dose of hydroxychloroquine combined with three predefined dose groups of palbociclib
  • RP2D dose of 100mg bid of hydroxychloroquine combined with palbociclib was selected for phase II clinical trial.
  • Guangzhou, Guangdong, China
    Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Jul 19, 2023

Re-EValuating Inhibition of Stress Erosions - COVID-19 Cohort

Recruiting
  • COVID-19
  • GastroIntestinal Bleeding
  • Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial (NCT03374800)
  • Hamilton, Ontario, Canada
    St Joseph's Healthcare Hamilton
Feb 6, 2023

Metastatic Soft-tissue Sarcoma Trial in United States (Cabozantinib, Nivolumab, Ipilimumab)

Recruiting
  • Metastatic Soft-tissue Sarcoma
  • Stanford, California
  • +3 more
Jan 10, 2023

COVID-19 Trial in Brandenburg an der Havel (Palbociclib)

Withdrawn
  • COVID-19
  • Brandenburg an der Havel, Germany
    Universitätsklinikum Brandenburg an der Havel
Nov 3, 2022

Nasal Polyps, Asthma, Aspirin-Induced, Aspirin-Exacerbated Respiratory Disease Trial in Boston (Dupilumab, Placebo)

Not yet recruiting
  • Nasal Polyps
  • +3 more
  • Boston, Massachusetts
    Brigham and Women's Hospital
Oct 7, 2022

Type 2 Diabetes, Hypertension Trial in Nashville (Placebo, Sitagliptin, Aprepitant)

Completed
  • Type 2 Diabetes Mellitus
  • Hypertension
  • Placebo
  • +3 more
  • Nashville, Tennessee
    Vanderbilt University
Feb 8, 2022

Asthma Trial in Ann Arbor (Dupilumab)

Recruiting
  • Asthma
  • Ann Arbor, Michigan
    University of Michigan
Mar 3, 2022

Leptomeningeal Metastasis, NSCLC Stage IV, Melanoma Stage IV Trial in Geneva, St Gallen, Zurich (intrathecal nivolumab and

Recruiting
  • Leptomeningeal Metastasis
  • +2 more
  • intrathecal nivolumab and intrathecal ipilimumab
  • Geneva, Switzerland
  • +2 more
Dec 18, 2022

Recurrent Glioblastoma, Recurrent Astrocytoma, Recurrent Oligodendroglioma Trial in Oklahoma City (Niraparib)

Recruiting
  • Recurrent Glioblastoma
  • +3 more
  • Oklahoma City, Oklahoma
    Stephenson Cancer Center
Jul 20, 2022

Type 2 Diabetes, Diabetic Kidney Disease Trial in Aurora, Boston, Ann Arbor (canagliflozin, Aminohippurate Sodium Inj 20%)

Recruiting
  • Type 2 Diabetes
  • Diabetic Kidney Disease
  • Aurora, Colorado
  • +3 more
Aug 17, 2022

SARS-CoV-2 Virus Infection Trial in United Kingdom (VLA2001, AZD1222, VLA2001 - adolescent part)

Active, not recruiting
  • SARS-CoV-2 Virus Infection
  • VLA2001
  • +3 more
  • Barnsley, United Kingdom
  • +30 more
Oct 17, 2022

Chordoma Trial in Essen, Heidelberg, Ulm (Palbociclib)

Recruiting
  • Chordoma
  • Essen, Germany
  • +2 more
Dec 6, 2021

Scleroderma, Systemic Trial in Athens (MABp1 (Bermekimab) OR Placebo, MABp1 (Bermekimab))

Completed
  • Scleroderma, Systemic
  • MABp1 (Bermekimab) OR Placebo
  • MABp1 (Bermekimab)
  • Athens, Attiki, Greece
  • +1 more
Sep 28, 2022

NSCLC Stage IV, Melanoma Stage IV, Unresectable Melanoma Trial in Montréal (Camu Camu Capsules (Camu Camu powder encapsulated

Recruiting
  • NSCLC Stage IV
  • +3 more
  • Camu Camu Capsules (Camu Camu powder encapsulated (500mg each) + ICI
  • Montréal, Quebec, Canada
    Centre hospitalier de l'Université de Montréal (CHUM)
Jul 18, 2022

COVID-19 Trial in New Haven (PF-06650833, Placebo)

Terminated
  • COVID-19
  • New Haven, Connecticut
    Yale New Haven Hospital
Oct 18, 2021

Asthma Trial in Sacramento (Roflumilast, Placebo)

Recruiting
  • Asthma
  • Sacramento, California
    UC Davis
Jan 31, 2022

Fungal Infection Trial in Groningen (APX001, Itraconazole, Rifampin)

Completed
  • Fungal Infection
  • Groningen, Netherlands
    PRA-EDS
Oct 27, 2021

Healthy Volunteers Trial in Berlin (Zoliflodacin Patheon)

Recruiting
  • Healthy Volunteers
  • Zoliflodacin Patheon
  • Berlin, Germany
    Parexel Early Phase Clinical Unit
Nov 22, 2022

Breast Cancer Trial in Amsterdam, Groningen (FES-PET scan, and possibly one additional visit for an FDG-PET)

Recruiting
  • Breast Cancer
  • FES-PET scan, and possibly one additional visit for an FDG-PET
  • Amsterdam, Netherlands
  • +1 more
Jan 11, 2022

Associated With First-Line CDK4/6 Inhibition and Hormonal

Not yet recruiting
  • Metastatic Breast Cancer
  • Palbociclib + aromatase inhibitor
  • Aromatase inhibitor
  • New York, New York
    Pfizer
Sep 7, 2021

Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia Trial in Duarte (Cobimetinib, Enasidenib Mesylate)

Not yet recruiting
  • Recurrent Acute Myeloid Leukemia
  • Refractory Acute Myeloid Leukemia
  • Duarte, California
    City of Hope Medical Center
Jun 28, 2022

Coronavirus Infection, Type 2 Diabetes Trial in Miami (Linagliptin, Insulin regimen)

Withdrawn
  • Coronavirus Infection
  • Type 2 Diabetes
  • Miami, Florida
    University of Miami
Jun 7, 2021